Managing peripheral neuropathy in private practice can be one of the most frustrating clinical experiences for Primary Care Physicians and Neurologists alike.As you know, drug costs and patient compliance, as well as medication side effects have left us all wishing there were more as doctors that we could do for our patients. Well, now there is!

KLF4 also known as gut-enriched Kruppel-like factor (GKLF) acts as a transcriptional activator or repressor depending on the promoter context and/or cooperation with other transcription factors.

OCT4 is a mammalian POU transcription factor expressed by early embryo cells and germ cells. It belongs to the POU transcription factor family.

Nanog also known as Homeobox transcription factor Nanog is a homeobox transcription factor belonging to the Nanog homeobox family with a homeobox DNA-binding domain.

SOX2 belongs to a family of DNA binding High-Mobility group domain transcription factor proteins, which has been identified as a key player in both in regulating embryonic development as well as in determining cell fates.

Truth in Science Counts is a multimedia, interactive, Adventure in Science, exploring the Universe we live in.

Socialization is not as easy as it sounds, and to completely understand and it is an on going process throughout life. There are a lot of different parts to socialization so we will try to cover them as brief as possible. The infamous psychologist Sigmund Freud stated that biology pays a significant part in human development. He believed that humans have two simple needs, and the first is the need to bond, and the second is the aggressive drive in which he coined as death instinct. Freud stated that these are two opposing forces that works in the unconscious level and causes some internal torment. The unconscious theory of psychology is both controversial and debatable because there is really no concrete proof that it exists. He also combined personality and the basic drives into three separate parts which are known as the id, ego, and superego. The id is an individual's basic drives in the unconscious mind, and it demands attention from people.

As one of the largest and most diverse protein families in nature, the G-protein coupled receptor (GPCR) superfamily play important roles in a variety of biological and pathological processes such as development and proliferation, neuromodulation, angiogenesis, metabolic disorders, inflammation, and viral infection. Not surprisingly, it is one of the most targeted protein families in pharmaceutical research today(Schlyer 2006).

NF-kB (Nuclear Factor-KappaB) is a heterodimeric protein composed of different combinations of members of the Rel family of transcription factors. The Rel/NF-kB family of transcription factors are involved mainly in stress-induced, immune, and inflammatory responses. For more details read out the article:

Early development and differentiation of nascent T cells inside the thymus is a complex and remarkable mechanism.These types of T-cells require a different strategy to tame their autoimmune potential. One of many immunotolerance mechanisms that immune system has developed to distinguish between self and non-self antigens is regulatory T cells or Tregs. For more details read out the article: